Figure 3 - full size

 

Figure 3.
Fig. 3. Stereo diagram of the TAR RNA 3-nt bulge region showing the direct and indirect ligands of Ca1, Ca2, and Ca3. Water molecules are colored cyan. Solid yellow bonds denote inner-sphere ligand interactions with the RNA, and black dashed bonds represent outer-sphere coordination. Additional water molecules binding in the bulge region have been omitted for clarity.