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Figure 3.
Figure 3. Structure of the Coiled-Coil Domain of STAT-1The
polypeptide backbone of the four helices is shown as a gray
ribbon. The directions of the helices are indicated by arrows.
All the side chains in the domain are depicted in the figure and
are colored red (acidic), blue (basic), orange (polar), and
yellow (hydrophobic). Note the clusters of acidic and basic
residues on the surface. The only significant cluster of
hydrophobic side chains on the surface corresponds to the site
of attachment to the DNA-binding domain and is indicated by a
dotted line.
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