Figure 4 - full size

Figure 4. Fig. 4. View into the major groove of stem 2 showing the distinct turn in loop 1. The coloring scheme is identical to that of Fig. 2. U24 and U23 are not involved in base-pairing interactions with the opposite bases of A41 and C42. Nucleotides C21 and U22, spanning the major groove, are drawn in thin lines. The curved arrow denotes the direction of the RNA chain.

The above figure is reprinted by permission from the AAAs: Science (1998, 280, 434-438) copyright 1998.