Figure 3 - full size

Figure 3. Fig. 3. Schematic diagram of FHIT in (A) apo, (B) AMP-CP substrate analog, (C) adenosine-tungstate transition-state^ analog, and (D) adenosine-sulfate product complexed forms. As in Fig. 2, hydrogen-bonding interactions are depicted by dotted^ lines. A subset of residues is shown superimposed on the C backbone^ cardinal spline of each respective structure.

The above figure is reprinted by permission from the AAAs: Science (1997, 278, 286-290) copyright 1997.