Figure 3.
Fig. 3. Experimental density (2F[o] F[c]) for
the 186-loop of tPA, showing the cluster of Arg186A, Gln186C,
His188. Gly19 of the activation peptide is adjacent to this loop
(lower right), as is the strand His159-Arg161 (bottom).
Orientation as in Fig. 1.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(1997,
272,
21713-21719)
copyright 1997.
F[c]) for
the 186-loop of tPA, showing the cluster of Arg186A, Gln186C,
His188. Gly19 of the activation peptide is adjacent to this loop
(lower right), as is the strand His159-Arg161 (bottom).
Orientation as in Fig. 1.