Figure 3 - full size

Figure 3. Figure 3. Comparison of Bound Nucleotide Conformations in Hsc70 and Hsp90Conformations of ADP bound to (a) Hsc70 ([13]) and (b) Hsp90. The N1, N6, which make specific contacts in the ADP/ATP-binding pocket, are indicated, as is the adenine base C8 atom, which is unhindered in the Hsc70-bound conformation but hindered in the Hsp90-bound conformation.

The above figure is reprinted by permission from Cell Press: Cell (1997, 90, 65-75) copyright 1997.