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Figure 3.
Fig. 3. The zinc binding site of SEA co-crystallized with
Zn2+. A, tetrahedral zinc co-ordination in molecule one (yellow)
in the asymmetric unit. Note that the use of His61 from the
neighboring molecule (cyan) as zinc ligand leads to the loop
59-63, absent in the SEA-Cd^2+ structure, here becoming ordered.
B, tetrahedral zinc co-ordination in the second molecule of the
asymmetric unit. The three high affinity SEA ligands are used
and in addition a water molecule^ (H[2]O) is used as the fourth
Zn2+ ligand. The figures were drawn using Molscript (30) and
Raster3D^ (31).
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