|
Figure 3.
The cathepsin V-clitocypin complex. A, shown is the view
along the active site cleft. B, shown is the view perpendicular
to the active site cleft. The folds of cathepsin V and
clitocypin are shown in gray and red. The catalytic cysteine is
shown in yellow. Clitocypin binds into the active site of
cathepsin V in the orientation of a fallen tree with the trunk
and roots pointing sideways and up. The wedge shaped structure
fills the active site cleft along its whole length.
|