Figure 3 - full size

 

Figure 3.
Overlap of the receptor binding domains of H1, H2, and H3 HAs in complexes with receptor analogues. (A) The overlapped receptor binding sites of human HAs for H1 A/S.Carolina/1918, (blue), H2 A/Singapore/1/57, (yellow) and H3 A/Aichi/2/68, (22) (gray) in complex with human receptor analogue, LSTc. (B) The receptor binding domains of avian HAs for H1, A/dk/Alberta/76 (blue), H2, A/dk/Ontario/77 (yellow), and H3, A/dk/Ukraine/63 (25) (gray) in complex with human receptor analogue. The sialopentasaccharides are colored according to the HAs to which they are bound and some of the side-chains discussed in the text are shown in stick representation.