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Figure 3.
Fig. 3. Relaxed stereo diagram of the X-ray crystal
structures of the reduced and oxidized forms of the Ala66 →
Cys mutant (CPK coloring). (a) Molecule A in the asymmetric unit
of reduced Ala66 → Cys overlaid with wild-type FGF-1 (PDB code
1JQZ; light gray). (b) Molecule B in the asymmetric unit of
reduced Ala66 → Cys overlaid with wild-type FGF-1 (PDB code
1JQZ; light gray). (c) Molecule A of oxidized Ala66 → Cys
overlaid with wild-type FGF-1 (PDB code 1JQZ; light gray). (d)
Molecule A of oxidized Ala66 → Cys overlaid with FGF-23 (PDB
code 2P39; light gray), which contains Cys at equivalent
position Cys66 in FGF-1 and forms a disulfide with Cys at
equivalent position Cys83.
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