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Figure 3.
(a) Overview of protein L27 in relation to the A- and P-site
tRNAs (in green and purple, respectively). The protein (dark
blue) contains a globular domain and an N-terminal extension
that localizes between the 3' ends of the ribosomal tRNAs. (b)
Predicted interactions of protein L27 with the ribosomal
substrates and 23S RNA (light blue). The modeled interactions
were observed in both structures containing occupied A sites,
though the post-peptidyl-transfer structure is displayed here as
it contained moderately better electron density for L27. A
representative 3F[o] – 2F[c] electron density map is displayed
in blue. (c) Overview of protein L16 in relation to the
ribosomal substrates. The protein is located adjacent to the
elbow of the A-site tRNA. (d) Interactions between the conserved
residues Arg51 and Arg56 of protein L16 (dark blue) with the
backbone of the A-site tRNA (green). Representative 3F[o] –
2F[c] density, as determined in the pre-peptidyl-transfer
structure, is displayed in green for the region of the A-site
tRNA predicted to interact with L16.
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