Figure 3.
Figure 3 The uridyltransferase active site. (a) Binding of
GlcNAc-1-P (ball-and-stick model). Hydrogen bonds are shown as
dashed lines and the 2F[o] - F[c] electron density is contoured
at 1.0 .
(b) Comparison of GlcNAc-1-P (white outlined protein) and
UDP-GlcNAc (blue protein) binding and associated loop movement
within the uracil site. GlcNAc-1-P and UDP-GlcNAc molecules are
drawn as ball-and-stick models with white- and yellow-coloured C
atoms, respectively. Water molecules are drawn as red spheres
and are associated with the UDP-GlcNAc protein model.
The above figure is reprinted
by permission from the IUCr:
Acta Crystallogr D Biol Crystallogr
(2009,
65,
275-283)
copyright 2009.
.
(b) Comparison of GlcNAc-1-P (white outlined protein) and
UDP-GlcNAc (blue protein) binding and associated loop movement
within the uracil site. GlcNAc-1-P and UDP-GlcNAc molecules are
drawn as ball-and-stick models with white- and yellow-coloured C
atoms, respectively. Water molecules are drawn as red spheres
and are associated with the UDP-GlcNAc protein model.