Figure 3 - full size

 

Figure 3.
Figure 3. Residues 87–93 Pack Identically into Symmetry-Related HLA Binding Sites
The gp42 N-terminal residues that are immediately proximal to the CTLD extend similarly in the two copies of the gp42 molecules in the asymmetric unit and make identical packing interactions with the HLA binding site of a neighboring molecule.
(A) The overlay of the two gp42 molecules of the asymmetric unit is shown in beige, with the N-terminal residues in yellow stick representation that form this packing interaction with the neighboring gp42 (blue). The HLA binding site is indicated and the corresponding residues are shown as sticks.
(B) A zoomed-in view of this packing interaction is shown, along with the packing of residue F88 against hydrophobic HLA binding residues.

The above figure is reprinted by permission from Cell Press: Structure (2009, 17, 223-233) copyright 2009.