Figure 3 - full size

 

Figure 3.
Molecular mechanism for the catalysis by BC. A, modeled binding mode of ATP (in gray) in the active site of BC. The bicarbonate is in the appropriate location to initiate the reaction. B, schematic drawing of the catalytic mechanism of BC. Glu^296 and Arg^338 have crucial roles in this reaction.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2009, 284, 11690-11697) copyright 2009.