Figure 3 - full size

 

Figure 3.
Figure 3: Interactions of FMN analogues with the riboswitch. a, All-atom superposition of the ligand-binding pocket for riboflavin-bound (blue and green) and FMN-bound (grey) riboswitches. Nucleotides in green are positioned within hydrogen-bond distances of the ribityl moiety of riboflavin. b, Superposition of riboflavin-bound (blue) and roseoflavin-bound (pink and green) riboswitches, depicted as in a. c, Surface view inside of the FMN-bound riboswitch with large openings shown with red arrows.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2009, 458, 233-237) copyright 2009.