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Figure 3.
Details of the ADP and Zn-binding regions. (A) The
nucleotide-binding pocket. Main chain and carbons are colored
according the conserved motifs: motif 0 (yellow), motif I
(magenta), motif II (light blue), motif V (gray). (B) Overlay of
the Zn domains of RECQ1 (orange) and E. coli RecQ (gray). The
yellow/black spheres indicate the zinc ion, which nearly overlap
in the 2 structures. (C) Overlay of the WH domains of RECQ1
(red), WRN (blue), and E. coli RecQ (green). The β-hairpin
forming one of the wings and the hydrophobic residues at the
hairpin tip are highlighted.
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