Figure 3 - full size

 

Figure 3.
Figure 3: Open GLIC and closed ELIC structure comparison. a, Side view of the structural superposition. For the two subunits in the foreground, only the common core is depicted, in green for GLIC, in red for ELIC. Other subunits are in grey. The ECD rotation axes and the twist axis are depicted. The M4 helix is omitted for clarity. b, Close-up view of the interface between the ECD and the TMD (side view in left panel and upper view in right panel). c, Close-up of transmembrane helices M1–M3 viewed from the channel.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2009, 457, 111-114) copyright 2009.