Figure 3 - full size

 

Figure 3.
The electrostatic potential mapped to the surface of the Steap3 dimer. Positive potentials are in blue, negative potentials in red (±25 kT/e). Steap3-NADPH and the docked FMN from BVR-B are also shown. The orientation of the dimer and colors for NADPH are as in Fig. 1. FMN is similarly colored, but carbons are in cyan. Note the cleft running up the front side and across the top of the dimer interface. Because of the symmetry of the dimer, the cleft continues along the interface down the back side of the dimer.