Figure 3.
FIGURE 3. Views of the ligand-binding site of P450 2C8
illustrating interactions of (R)-felodipine (A and B) or
9-cis-retinoic acid (C and D) with the protein. The proximal
molecule of retinoic acid is designated as RA1, and the distal
molecule is labeled as RA2. The atom color code is the same as
described in the legend of Fig. 2.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2008,
283,
17227-17237)
copyright 2008.