Figure 3 - full size

 

Figure 3.
(a) The structure of genistein-bound ER Y537S is depicted as a ribbon diagram, showing only a portion of the molecule that interacts with the ligand. The closed interface between helix 11 and L7-8 is shown by a red circle.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Chem Biol (2008, 4, 241-247) copyright 2008.