Figure 3.
Figure 3. Overall structure of the hHyHEL-10 Fv–HEL and
mutant–HEL complexes. The structure of the three humanized
Fv–HEL complexes, whose C coordinates
of HEL are superimposed on the C coordinates
of HEL complexed with mHyHEL-10, is superposed on the structure
of Fv (gray). Red, hHyHEL-10 Fv–HEL complex; blue, HW47Y
Fv–HEL complex; green, HQ39KW47Y Fv–HEL complex. Generated
with PyMOL (DeLano Scientific).
The above figure is reprinted
by permission from the Protein Society:
Protein Sci
(2008,
17,
261-270)
copyright 2008.
coordinates
of HEL are superimposed on the C