Figure 3 - full size

 

Figure 3.
Molecular surface of the CERT START domain in complex with C[6]- (A), C[16]- (B), and C[18]- (C) ceramide cut at the level of the cavity, respectively. Ceramide molecules are drawn as sticks, in which yellow, blue, and red represent C, N, and O atoms, respectively. Hydrophobic and polar/charged amino acid residues inside the cavity are shown in green and blue, respectively. The outer surface and the cross-section of the CERT START domain are drawn in gray and in dark brown, respectively.