Figure 3.
(a) Structure of the anticodon-binding domain (stereo view).
Green, helices; blue, -strands;
yellow, tRNA; red, anticodon nucleotides; ball-and-stick models,
Glu418 and Glu420. (b) The recognition of the tRNA^Cys anticodon
loop in the SepRS–tRNA^Cys–O-phosphoserine complex (stereo
view). Pink and green mesh, |F[o] - F[c]| simulated-annealing
omit electron density maps (3.0 )
for the tRNA anticodon loop nucleotides and the SepRS
recognition residues, respectively. (c) Recognition of A36, G37
and A38. (d) Recognition of G34 and C35. Pink, the two residues
(Glu418 and Glu420) that were mutated for engineering.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(2007,
14,
272-279)
copyright 2007.
-strands;
yellow, tRNA; red, anticodon nucleotides; ball-and-stick models,
Glu418 and Glu420. (b) The recognition of the tRNA^Cys anticodon
loop in the SepRS–tRNA^Cys–O-phosphoserine complex (stereo
view). Pink and green mesh, |F[o] - F[c]| simulated-annealing
omit electron density maps (3.0 
)
for the tRNA anticodon loop nucleotides and the SepRS
recognition residues, respectively. (c) Recognition of A36, G37
and A38. (d) Recognition of G34 and C35. Pink, the two residues
(Glu418 and Glu420) that were mutated for engineering.