Figure 3.
Fig. 3. [(A) and (B)] Functional mutations map within the
phosphate binding tunnel, a large internal cavity that traverses
the subunit, shown in
red. The majority of known function-impairing mutants map to the
surface of this tunnel, positioned between the terminal
phosphate of the bound nucleotide and the putative
kinase-binding face. Two orthogonal views are shown.
The above figure is reprinted
by permission from the AAAs:
Science
(2007,
315,
1726-1729)
copyright 2007.
subunit, shown in
red. The majority of known function-impairing mutants map to the
surface of this tunnel, positioned between the terminal
phosphate of the bound nucleotide and the putative
kinase-binding face. Two orthogonal views are shown.