Figure 3 - full size

 

Figure 3.
FIGURE 3. Structure in the heme pocket of Cj-trHbP. A, a stereo view of the heme, of the proximal His(F8), and of the surrounding distal residues contacting the heme and stabilizing the bound cyanide. Hydrogen bonds within the distal residue cluster, including the heme ligand, are indicated with dashed lines. Residue His^46(E7) is shown in the closed and open (magenta) conformations. B, details of the heme distal site, including the C helix (top in the figure) and the E helix; for comparison, the C-E backbone region of group I C. eugametos trHbN (orange) is also displayed.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2006, 281, 37803-37812) copyright 2006.