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Figure 3.
Fig. 3. Active site of ARH3. (A) Coordination of Mg^2+ ions
in the orthorhombic crystal form of hARH3. Hydrogen bonds are
represented as dashed lines. (B) Superposition of the
Mg^2+-coordinating residues of the orthorhombic (gray) and
monoclinic crystal forms. Residue Asp-300 is slightly shifted
but retains its bidentate binding character, whereas Glu-25 of
the monoclinic crystal form is shifted by 1.8 Å with
respect to those of the orthorhombic crystal form. The residues
from the monoclinic crystal form are shown in color.
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