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Figure 3.
FIGURE 3. Details of ligand binding in nsP2Ox[ACT] and
His6-H167A[2FG]. Side-by-side view showing the active site in
the nsP2Ox[ACT] complex (A) and the His[6]-H167A[2FG] complex
(B). In B, the carbohydrate is positioned for oxidation at C3.
Firm interactions are noted for the C3 hydroxyl group and the
side chains of His^548 and Asn^593. The substrate loop is
highlighted in magenta. Atom-coloring scheme: carbon, beige
(protein), yellow (FAD), green (ligand); nitrogen, blue; oxygen,
red. C, superposition of the active sites in nsP2Ox[ACT] (beige)
and His[6]-H167A[2FG] (green).
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