Figure 3 - full size

 

Figure 3.
Figure 3. Hydrogen bond, C-H…O and C-H…π interactions are shown in the active site cavity of PR[V32I] for the major conformation of TMC114 (a) and the minor conformation (b). Interactions for the alternate conformations of TMC114 in PR and PR[M46L] are shown in the Supplementary Material.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2006, 363, 161-173) copyright 2006.