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Figure 3.
Fig. 3. Overlay of RedA, SphB, and KabC on actin. (A) RedA
(green sticks) and SphB (cyan sticks) are shown superimposed in
their actin-bound conformation on a surface drawing of actin.
Common actin residue contacts are shown in salmon. Residues
contacting RedA but not SphB are shown in yellow. Selected atoms
and the lactone ring of each toxin have been labeled for
reference. (B) RedA (green sticks) and KabC (yellow sticks) are
shown superimposed in their actin-bound conformation. Residues
that are common to the binding of both RedA and KabC are colored
salmon. KabC atom numbers are given primes ('). The coordinates
for KabC actin were obtained from Protein Data Bank entry 1QZ5
[PDB]
. Toxins were superimposed on actin by using the program
SUPERPOSE in CCP4.
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