|
Figure 3.
Model of the LCBD of myosin V. The light chains, which can be
either CaM or CaM-related molecules such as Mlc1p are colored
cyan (N-lobes) and magenta (C-lobes), and the six-IQ fragment of
the heavy chain is colored green. The LCBD of myosin V can be
conceptually subdivided into three semiindependent pairs of IQ
motifs, with little or no interactions between pairs. The
linkers between neighboring IQ pairs are 14 aa long, whereas the
linkers between IQs in a pair are 12 aa long. An enlargement
illustrates the interaction between light chains in a pair.
|