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Figure 3.
Figure 3 Comparison of cap-binding pockets. m7G-cap-binding
pockets of CBP20, eIF4E and the viral nucleoside
2'-O-methyltransferase (VP39) are presented in comparison to the
m[3]G-cap-binding pocket of snurportin1. Side chains of residues
interacting with the caps are depicted in ball-and-stick mode.
Atoms of the caps and the interacting side chains are coloured
as described in Figure 1, with the exception of carbon atoms of
the dinucleotide, which are shown in orange. In all presented
cases, the residues stacking the bases and those forming
hydrogen bonds with the cap bases are depicted. Hydrogen bonds
are shown as dashed grey lines.
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