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Figure 3.
FIG. 3. Comparison with NAGK structure. A, superposition of
the ribbon representations of the monomers of UMPKeco (blue,
with a stick model of UMP in cyan) and NAGK (yellow, with
N-acetyl glutamine and ADPNP in red; the helix homologous to
3
is pink). The cross-talk loop of UMPKeco is green, the flexible
loops close to ADPNP are magenta, and the extra -hairpins
of NAGK are orange. The orientation is close to that in Fig. 2A
but slightly modified to better see all ligands. B, the dimer of
NAGK. The orientation is slightly different from that in Fig. 2B
to give a better view of the interface.
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