Figure 3 - full size

 

Figure 3.
FIG. 3. Comparison with NAGK structure. A, superposition of the ribbon representations of the monomers of UMPKeco (blue, with a stick model of UMP in cyan) and NAGK (yellow, with N-acetyl glutamine and ADPNP in red; the helix homologous to 3 is pink). The cross-talk loop of UMPKeco is green, the flexible loops close to ADPNP are magenta, and the extra -hairpins of NAGK are orange. The orientation is close to that in Fig. 2A but slightly modified to better see all ligands. B, the dimer of NAGK. The orientation is slightly different from that in Fig. 2B to give a better view of the interface.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2005, 280, 25533-25540) copyright 2005.