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Figure 3.
Figure 3. Representations of the active sites in the five
complex structures (E2 (a), E2* (b), E3* (c), E4* (d), and E5*
(e)) showing the interactions between active-site functional
groups and the inhibitors (broken lines). Distances (in Å)
for the interactions are denoted adjacent to the broken lines.
Covalent cross-links between Lys65, His108, and Tyr159 (see
Materials and Methods) are shown in (a).
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