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Figure 3.
Figure 3. The Central Cavity at the Dimer-Dimer Interface
in Human Caspase-1The active site is indicated by orange
ellipses; the dimer-dimer interface is enclosed by a yellow
box.(A) Surface representation of the residues surrounding the
closed cavity in the enzyme complexed with an active-site
inhibitor.(B) Surface representation of the residues surrounding
the open cavity in the active-site ligand-free enzyme.
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