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Figure 3.
Figure 3. Solution structure of the RNA complex of TIS11d.
(a) Stereo view of the best 20 structures superposed on backbone
heavy atoms in ordered regions of the protein and RNA. The
protein backbone is blue, the RNA backbone red, and RNA bases
yellow. For clarity, only ordered regions of TIS11d (residues
153 -217) and RNA bases U2 -U9 are shown. (b) Ribbon
representation of a single structure, in the same orientation as
in a, showing the location and coordination of zinc in each of
the fingers. Colors are the same as in a, with the addition of
green side chains for the zinc-coordinating ligands. (c)
Backbone superposition of the structure ensembles of fingers 1
and 2. Finger 1 (Arg153 -Phe180) is dark blue (backbone), green
(zinc-coordinating side chains) and red (intercalating aromatic
rings); the bound RNA (U6, A7, U8, U9) is orange. The
corresponding colors for finger 2 are light blue, yellow, pink
and yellow. Figures were generated using MolMol50.
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