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Figure 3.
Figure 3 Analysis of the concave surface of Cvx. (a) Surface
representation of the Cvx tetramer. (b) Orientation of the
concave surface relative to the rest of the molecule.  -
and  -subunits
are coloured blue and red, respectively. The van der Waals
surface of the -heterodimer
is depicted in transparent grey and the concave surface with a
transparent brown tint. Relative orientations of views are
given. (c) Close-up view of the concave surface of the -heterodimer.
Residues contributing to charged patches are indicated. (d)
Schematic representation of the Cvx tetramer interaction with
protein ligand at the cell surface. The Cvx tetramer is depicted
as in Fig. 1-(a) with a 120° rotation about the horizontal.
Ligand molecules interacting at each concave surface are
depicted as transparent gold spheres. The cell surface is
depicted in grey.
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