Figure 3.
FIG. 3. The least squares superimposed structures of
wild-type human Mn-SOD (purple) and H30N/Y166F Mn-SOD (yellow)
showing residues in the active site. Similar to Asn171(B) in the
single mutant, this side chain turned toward subunit A in the
double mutant, but there is no hydrogen bond between Asn171(B)
and Asn30(A). Instead, the N -2 of Asn30 formed a
weak hydrogen bond with the phenolic OH of Tyr34.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2004,
279,
5861-5866)
copyright 2004.
-2 of Asn30 formed a
weak hydrogen bond with the phenolic OH of Tyr34.