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Figure 3.
FIG. 3. Structural transition of CLIC1 between the
monomeric and the dimeric forms. Representations of reduced
monomeric form of CLIC1 (A) and a subunit of the oxidized
dimeric form (B). C, backbone superposition of CLIC1 for the
reduced monomeric (green) and the oxidized dimeric (magenta)
states. Ramachandran distances for residues 23-234 are mapped
onto the backbone of the monomeric (D) and dimeric (E) forms.
The color gradient, from gray to pink represents Ramachandran
distances from 0° to 180°. Residues not observed in the
dimer are colored gold. F, Ramachandran plot of residues within
the N-domain with Ramachandran distances greater than 35^0
between the two structures. Monomer - co-ordinates are plotted
as orange squares, and dimer co-ordinates are in black with a
connecting line. The figures were made with SETOR (25),
MOLSCRIPT (26), RASTER3D (27), and GRASP (29).
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