Figure 3 - full size

 

Figure 3.
FIG. 3. Structural transition of CLIC1 between the monomeric and the dimeric forms. Representations of reduced monomeric form of CLIC1 (A) and a subunit of the oxidized dimeric form (B). C, backbone superposition of CLIC1 for the reduced monomeric (green) and the oxidized dimeric (magenta) states. Ramachandran distances for residues 23-234 are mapped onto the backbone of the monomeric (D) and dimeric (E) forms. The color gradient, from gray to pink represents Ramachandran distances from 0° to 180°. Residues not observed in the dimer are colored gold. F, Ramachandran plot of residues within the N-domain with Ramachandran distances greater than 35^0 between the two structures. Monomer - co-ordinates are plotted as orange squares, and dimer co-ordinates are in black with a connecting line. The figures were made with SETOR (25), MOLSCRIPT (26), RASTER3D (27), and GRASP (29).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2004, 279, 9298-9305) copyright 2004.