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Figure 3.
Figure 3. Hydrogen Bonding Contacts between Tdp1 and the
Vanadate-Peptide-DNA Substrate Transition State AnalogTdp1,
peptide, and DNA are colored as in Figure 1A, with the vanadate
moiety in green and hydrogen bonds indicated by dashed lines.
Residues 232–242 of Tdp1 have been omitted for clarity.
Hydrogen bonds to the vanadate moiety are displayed in (A),
hydrogen bonds to the peptide moiety are displayed in (B), and
hydrogen bonds to the DNA moiety in (C).
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