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Figure 3.
Figure 3 (A) Molecular surface rendering of the Ohr dimer. The
catalytically active Cys60 (shown in yellow) lies at the bottom
of the active-site pocket, which is outlined with hydrophobic
residues (shown in green). (B) Stereo view of the Ohr active
site. Hydrogen bonds are depicted by light blue, dashed lines.
Monomer A (shown in green) contributes Cys60 and Cys124 residues
(also in green) and monomer B (shown in purple) contributes
Arg18 and Glu50 residues (also in purple) to the active site.
The DTT molecule (orange) is depicted in a ball-and-stick
format. Nitrogen atoms are dark blue, oxygen atoms are red and
sulfur atoms are yellow. (C) Representative region of the
density-modified experimental electron density map showing the
active-site pocket in the Ohr structure (the refined model)
contoured at 1.5  .
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