|
Figure 5.
Figure 5. TcTS-Lactose Interactions(A) Electron density
(2Fo-Fc) map, contoured at 1 σ, of the lactose binding site in
the triclinic crystal form. The loop containing Gly145/Gly146
from a neighbor molecule in the crystal is also shown.(B)
Electron density (2Fo-Fc) map, contoured at 1 σ, showing the
lactose and DANA molecules in the ternary complex.(C) Schematic
diagram showing protein-carbohydrate hydrogen bonding
interactions.(D) Stacking interactions of the lactose moiety
with the aromatic rings of Trp312 and Tyr119 in the ternary
complex.
|
