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Figure 3.
Fig. 3. Schematic diagram showing the pattern of NH-NH
and C  H-C H NOEs
predicted for conformations of M[H]  [2]m (a)
lacking and (b) containing the bulge
involving residues 53 and 54. C H-C H region
(c) and NH-NH region (d) of a 1H-1H NOESY spectrum of M[H] [2]m
acquired at pH 5.7, 37°C, in D[2]O and H[2]O, respectively.
Crosspeaks consistent with the presence of the bulge in
solution are marked in bold and underlined. Crosspeaks expected
were M[H] [2]m to
adopt a conformation in solution identical to that in a are
shown as solid circles.
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