Figure 3.
Figure 3 Interactions between tyrosyl-tRNA synthetase and
tRNA^tyr. (A) The C-terminal domain (orange) binds in the elbow
between the long variable arm and the anti-codon stem of the
tRNA (red backbone, green bases). The anti-codon stem loop
interacts with both the C-terminal domain and the -helical
domain (pink). The tRNA makes no contact with the catalytic
domain of the same subunit (cyan). (B) The unusual conformation
of the anti-codon triplet in which Ade-36 is stacked on Gua-34,
while Psu-35 bulges out. (C) Base-specific interactions of
Asp-259 from the -helical
domain with Gua-34 and Asp-423 from the C-terminal domain with
Psu-35.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2002,
21,
3829-3840)
copyright 2002.
-helical
domain (pink). The tRNA makes no contact with the catalytic
domain of the same subunit (cyan). (B) The unusual conformation
of the anti-codon triplet in which Ade-36 is stacked on Gua-34,
while Psu-35 bulges out. (C) Base-specific interactions of
Asp-259 from the