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Figure 3.
Fig. 3. Active site of the abzyme. (Left) 10F11 in
complex with OXY (compound 6). The hydrogen bonding network is
shown as dotted lines. (Right) Surface representation of the
binding pocket of Fab 10F11 with the transition state analogue
BCN (compound 4) of the retro-Diels-Alder reaction. View is from
the top of the binding site showing the fit of the ligand BCN.
The light pink transparent surface represents V[L] and the light
blue transparent surface represents V[H]. Note the presence of
water molecules inside the pocket. Figure prepared with DINO
(http://www.dino3d.org).
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