Figure 3 - full size

Figure 3. Figure 3. The PtdCho-binding pocket. a, Views of the solvent accessible volume of the binding pocket, separated by a 90° rotation. b, Stereo view of the interactions of PC-TP with the glycerol-3-phosphorylcholine moiety of PLPC (yellow). The structure of DLPC from the PC-TP−DLPC complex is superimposed (gray). c, Stereo view of the interactions of the phosphorylcholine quaternary amine with PC-TP (yellow) and the trimethyllysine residue of the histone H3 tail with HP1 (ref. 24) (gray). The residues of the three-walled aromatic cage of PC-TP are labeled.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Biol (2002, 9, 507-511) copyright 2002.