Figure 3 - full size

 

Figure 3.
Figure 3 DBD-C modeled on a ssDNA molecule derived from the DBD-AB/ssDNA co-crystal structure. The DBD-C was aligned with DBD-B as shown in Figure 2C and then docked onto the 3 nt DBD-B binding site (shown in red). Side chains in DBD-C (the position for Y581 is putative) that are orientated to interact with the sugar-phosphate backbone are colored in green and blue (for carbon and nitrogen atoms, respectively), and those in position to hydrogen bond, or stack with, DNA bases are yellow. Putative hydrogen bonds with the phosphate groups are shown as dashed lines. The position of conserved C486 is shown as a reference.

The above figure is reprinted from an Open Access publication published by Macmillan Publishers Ltd: EMBO J (2002, 21, 1855-1863) copyright 2002.