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Figure 3.
Fig. 3. Comparison of KSHV Bcl-2 (A) to Bcl-x[L] (B) and
to Bcl-2 (C). Residues of the hydrophobic groove that are
homologous to those that contact the Bak and Bad peptides when
complexed to Bcl-x[L] are shown along with the tryptophan
residue of the NWGR sequence. To emphasize the differences in
the structured regions of the proteins, we have made our
comparisons to truncated forms of Bcl-2 and Bcl-x[L] (17, 18).
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