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Figure 3.
Fig. 3. Interaction of  -amanitin
with pol II. (A) The chemical structure of -amanitin,
with residues of pol II that lie within 4 Å [determined by
using CONTACT (26)] placed near the closest contact. The C s of -amanitin
are labeled with blue numbers. Hydrogen bonds are shown as
dashed lines with the distances indicated. (B) Stereoview of the
-amanitin
binding pocket. Ball and stick models of -amanitin
(red bonds) and of pol II residues within 4 Å (gray bonds)
are shown. Rpb1 from A700 to A809 (funnel region) is light
green. Rpb1 from A810 to A825 (bridge helix) is dark green. Rpb2
from B760 to B769 is blue. This figure was generated by using
BOBSCRIPT and RASTER3D (21-23).
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