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Figure 3.
Figure 3. A model of the rgRGS -G  [13]
complex. a, rgRGS domain is colored according to the scheme
in Fig. 1, and G  [13]
is colored gray. Switch regions of G [13]
are shown in plum. Residues 124 -129 in G [13]
could not be modeled reliably and so were omitted from the
model. b, Putative contacts between p115RhoGEF rgRGS domain and
G [13]
L3 - 3
and L5 segments of rgRGS are colored yellow and green,
respectively; switch I and switch II of G [13]
are colored plum. Side chains proposed to form specific contacts
are depicted as ball-and-stick models. Oxygen, nitrogen and
carbon atoms are colored red, blue and black, respectively.
Putative hydrogen bonds are indicated by dotted lines. c,
Structure of RGS4 -G [i1]
complex11 is shown in the same orientation and color scheme.
GDP, AlF[4]^- and the catalytic water molecule as bound in the
active site of G [i1]
are shown as ball-and-stick models.
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