Figure 3 - full size

 

Figure 3.
Fig. 3. Local structure of the reduced form around Fe---S cluster and Leu 41 in its open conformation (open water gate). Placing the side chain of Leu 41 away from Cys 9 S> allows the string of water molecules to approach the Cys 9 S>, with the first water forming a hydrogen bond with Cys 9 S>.

The above figure is reprinted from an Open Access publication published by the Protein Society: Protein Sci (2001, 10, 613-621) copyright 2001.